|
rs861539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
XRCC3 Thr241Met gene polymorphism was associated with osteosarcoma risk, but XRCC3 Thr241Met CC genotype was not associated with Enneking stage, tumor location, and tumor metastasis.
|
30539867 |
2018 |
|
rs121913364
|
|
|
0.020 |
GeneticVariation |
BEFREE |
With a median follow-up of 19.6 months, no structural or biochemical recurrence or metastases were found in patients with an isolated BRAF(K601E) mutation.
|
26422023 |
2016 |
|
rs2250889
|
|
|
0.020 |
GeneticVariation |
BEFREE |
When we examined the combined effect of R279Q and P574R and used the 279R and 574P as the risk alleles, a significantly increased risk of lung cancer was associated with both the genotypes containing "1 to 2 risk alleles" (adjusted OR, 2.16; 95% CI, 1.30-3.59) and containing ">2 risk alleles" (adjusted OR, 2.44; 95% CI, 1.48-4.03), and it was more pronounced in 290 lung cancer cases with metastasis [adjusted OR, 2.30 (95% CI, 1.09-4.85) for the 1 to 2 risk alleles subgroup and adjusted OR, 2.82 (95% CI, 1.35-5.88) for the >2 risk alleles subgroup], compared with those without any risk alleles.
|
16061858 |
2005 |
|
rs41291957
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When stratification analysis was done by different variables, such as tumor size, tumor site, differentiated status, clinical stage, and metastasis status, we found that patients with the mutant allele of rs41291957 had an increased risk to develop a tumor size larger than 5 cm.
|
23628392 |
2013 |
|
rs1801157
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We were also unable to find a correlation between rs1801157 and different prognostic markers such as metastasis development or disease-free survival time.
|
17982648 |
2007 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore analyzed the correlation of BRAF V600E and ERK-activation in 20 malignant melanomas and 21 subsequently evolved, paired metastases of the same donor by BRAF exon 15 DNA sequencing and phospho-specific immunohistochemistry for ERK.
|
20605766 |
2010 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We therefore analyzed the correlation of BRAF V600E and ERK-activation in 20 malignant melanomas and 21 subsequently evolved, paired metastases of the same donor by BRAF exon 15 DNA sequencing and phospho-specific immunohistochemistry for ERK.
|
20605766 |
2010 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We successfully treated a BRAF V600E-mutated anaplastic oligoastrocytoma with multiple extraneural metastases with vemurafenib and everolimus.
|
30462564 |
2019 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We successfully treated a BRAF V600E-mutated anaplastic oligoastrocytoma with multiple extraneural metastases with vemurafenib and everolimus.
|
30462564 |
2019 |
|
rs629367
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that the pri-let-7 rs629367 SNP could be used as a predictor of recurrence and metastasis after TACE for patients with PLC.
|
29627220 |
2018 |
|
rs1370041903
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We showed that, in one patient with pancreatic cancer, the expression of a truncated form of SPOP (p.Q360*) lacking the nuclear localization signal led to nuclear accumulation of NANOG, which promoted growth and metastasis of pancreatic cancer cells.
|
31624231 |
2019 |
|
rs1057519902
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation.
|
31139567 |
2019 |
|
rs1553260624
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report the case of a 17-year-old female with an H3F3A G34R mutated infiltrative glioma who developed painful osseous metastases to her pelvis and spine within 3 months of clinical presentation.
|
31139567 |
2019 |
|
rs1205
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We previously showed the association between C-reactive protein (CRP) 1846C>T (rs1205) polymorphism and LN metastasis in esophageal, non-small cell lung, and breast cancers.
|
26310275 |
2015 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We present a case of a 56-year old woman with a history of stage IIIA malignant melanoma resected in 2004 that was diagnosed in May 2013 with BRAF V600E-mutated metastatic disease (left arm mass, lungs and adrenal glands).
|
25576527 |
2015 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We present a case of a 56-year old woman with a history of stage IIIA malignant melanoma resected in 2004 that was diagnosed in May 2013 with BRAF V600E-mutated metastatic disease (left arm mass, lungs and adrenal glands).
|
25576527 |
2015 |
|
rs1458766475
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We postulated that some polymorphisms within the E-selectin gene, especially the S128R polymorphism, may increase the risk of metastases by facilitating adhesion of tumour cells to the endothelium.
|
19361981 |
2009 |
|
rs5361
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We postulated that some polymorphisms within the E-selectin gene, especially the S128R polymorphism, may increase the risk of metastases by facilitating adhesion of tumour cells to the endothelium.
|
19361981 |
2009 |
|
rs6691378
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed that HCC patients had lower frequencies of <i>CHI3L1</i> rs6691378 polymorphisms with the variant genotype GA+AA than the wild-type carriers with distant metastasis and positive HBsAg did.
|
28260989 |
2017 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We observed mutations resulting in the V599E amino-acid substitution in 41 of 60 (68%) melanoma metastases, 4 of 5 (80%) primary melanomas and, unexpectedly, in 63 of 77 (82%) nevi.
|
12447372 |
2003 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We observed mutations resulting in the V599E amino-acid substitution in 41 of 60 (68%) melanoma metastases, 4 of 5 (80%) primary melanomas and, unexpectedly, in 63 of 77 (82%) nevi.
|
12447372 |
2003 |
|
rs11016879
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We noted higher risk of nodal metastasis in rs11016879 AA homozygotes.
|
29370316 |
2018 |
|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated whether the presence of a BRAF V600E mutation is differentially associated with sites and appearance of metastatic disease in patients matched by primary tumor location.
|
27956538 |
2016 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated whether the presence of a BRAF V600E mutation is differentially associated with sites and appearance of metastatic disease in patients matched by primary tumor location.
|
27956538 |
2016 |
|
rs34296044
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated the relationship of single nucleotide polymorphisms (SNPs) at exon 10 (T439M) and exon 13 (P757L) of the EXO1 gene with development, progression and metastasis of colorectal cancer.
|
15550454 |
2005 |